AROPE : Early Ovarian Reserve Decreased : Impact of Exposure to Persistent Endocrine Disruptors and Organic Solvents

Inclusion Criteria : The cases will be: * women among couples consulting for infertility in 4 centers for medically assisted procreation (AMP) performing in vitro fertilization in the Brittany Pays de Loire region: the university hospital (CHU) of BREST, the CHU of RENNES, the La Sagesse clinic in RENNES and the CHU de NANTES, * having at least one characteristic of alteration of the ovarian reserve: a total number of antral follicles (left ovary + right ovary) less than 7 and / or a blood level of anti-Müllerian hormone (AMH) less than or equal to 1 , 1 ng / ml, * age between 18 and 40 years old, * with, in the event of past stimulation, at least one month since the last stimulation at the time of the blood and urine samples, * having signed a free and informed consent. For each case, two controls will be included with a pairing on the center and on the age group of 5 years (frequency pairing). It will be : * women among couples consulting for infertility in 4 centers for medically assisted procreation (AMP) performing in vitro fertilization in the Brittany Pays de Loire region: the university hospital (CHU) of BREST, the CHU of RENNES, the La Sagesse clinic in RENNES and the CHU de NANTES, * whose infertility assessment is strictly normal (AMH between 1.5 and 5 ng / ml, without genital malformation and with a menstrual cycle between 26 and 35 days), * age between 18 and 40 years old, * with, in the event of past stimulation, at least one month since the last stimulation at the time of the blood and urine samples, * having signed a free and informed consent. The non-inclusion criteria for cases and witnesses will be: * ovarian endometriosis, * polycystic ovary syndrome, * a history of adnexal surgery, * a history of cancer with chemotherapy or radiotherapy, * morbid obesity (BMI ≥ 35 kg / m²), * a chromosomal genetic syndrome (Turner and Fragile X) * adults who are the subject of legal protection (safeguard of justice, curatorship, guardianship) and persons deprived of their liberty.