Traditional Chinese Medicine Combined With Standard Triple Region for Eradication of Helicobacter Pylori

Inclusion Criteria: * those who met chronic gastritis (chronic superficial gastritis and chronic atrophic gastritis) diagnostic criteria; * aged between 18-65 years old; * positive H. pylori infection confirmed by two or more methods of different * principles (stop using PPI, H2RA, bismuth, and antibiotics since two weeks before examination); * patients were informed consent and willing to accept corresponding treatments. Exclusion criteria: * Patients having chronic atrophic gastritis with severe dysplasia, upper gastrointestinal bleeding, peptic ulcers, and gastrointestinal tumors; * digestive organic disease (such as chronic pancreatitis, cirrhosis, etc.), or systemic diseases affecting intestinal motility (such as hyperthyroidism, diabetes mellitus, chronic renal insufficiency, mental, and neurological diseases, etc.); * those who were accompanied by serious heart, liver and other major organs lesions, blood diseases, and cancer (ALT, AST two times higher than normal value); * those who had taken medicines that might affect H. pylori detection results within two weeks (antacids, H2RA, PPIs, bismuth and antibiotics, etc.); * pregnant and lactating women; patients with history of systematic and neuropsychiatric disorders; those who had history of any drug allergy; and those who were participating in other clinical trials.