To describe the natural history of the coronary atherosclerotic plaque development and progression over time by CCTA with demographic and laboratory data for refinement of risk stratification of patients referred for CCTA.
All PARADIGM study patients underwent initial and follow-up CCTA based on order from their primary physician. Demographic data, targeted medical history, cardiovascular risk factors, and laboratory data was prospectively collected in electronic case report forms (eCRFs) at the time of the initial CCTA and at the time of follow-up CCTA.
Study Type
OBSERVATIONAL
Enrollment
2,000
Change in plaque volume and composition detected by follow up CCTA
Time frame: 2 years
Cardiac mortality (yes or no)
Time frame: 2 years
Myocardial infarction (yes or no)
Time frame: 2 years
Unstable angina requiring hospitalization (yes or no)
Time frame: 2 years
Revascularization (yes or no)
Time frame: 2 years
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