"Holding-cuddling" plus oral sucrose versus oral sucrose for reducing venipuncture pain in newborns and infants. Neonates and infants routinely undergo venipuncture in pediatric and neonatal intensive care units. Such procedure is painful and several units administer 24% oral sucrose with pacifier during venipuncture, as this non-pharmacological intervention is considered safe and effective for procedural pain relief in infants from birth to 3 months of age. However, several studies point out that further research is needed to assess its efficacy in combination with other behavioral interventions for analgesia during painful procedures. Current knowledge suggests that multisensorial stimulation associated with oral sucrose could allow even more effective analgesia. To date, the studied stimulation strategies are based on massage, voice, eye contact and fragrance during heel prick. The "holding-cuddling" - that is the fact of holding the child in a safe, reassuring and warm position during the examination or medical intervention is promoted by various hospitals in order to favor the comfort of all the caregivers during such a procedures. This intervention should be primarily parents-driven but, in case of unavailability, it can be performed by the nursing staff. The hypothesis of this study is that the combination of "holding-cuddling" plus oral sucrose in more effective than oral sucrose in diminishing behavioral pain response during a venipuncture in newborns or infants less than three-month-old.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
68
The "Holding-cuddling" is started 5 minutes before veinipuncture.
The sucrose adminstration is started 2 minutes before veinipuncture.
Evolution of Pain
Measure of pain by DAN scale at the time of the veinopuncture
Time frame: At 0 and 30 seconds after the veinopuncture
Cardiac Frequency
Measure of the cardiac frequency at the time of the veinopuncture and 30 seconds after
Time frame: At 0 and 30 seconds after veinopuncture
Oxygen saturation
Measure of the oxygen saturation at the time of the veinopuncture and 30 seconds after
Time frame: At 0 and 30 seconds after veinopuncture
Pain at 1 min
Measure of pain by DAN scale 1 minute after veinopuncture
Time frame: 1 min after veinopincture
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