Safety and Immunogenicity Study of Quadrivalent Influenza Virus Vaccine in Healthy People Aged Years 3-60

Inclusion Criteria: * healthy subjects more than 3 years old, and the subjects can be informed consent, and sign the informed consent. * the subjects and his guardians can obey the demands of the scheme . * Axillary temperature less than 37℃ Exclusion Criteria: * The people who has flu or influenza-like symptoms(fever \<axillary temperature ≥38 ℃\>, cough or sore throat) within 3 months * The people who has vaccinated influenza vaccine in 3years. * The people who has a vaccine allergies, or who allergic to any kind of composition in experimental vaccine, such as eggs, ovalbumin etc. * The people who has serious side effects to vaccine, such as allergy, urticaria, skin eczema, dyspnea, angioneurotic edema or abdominal pain. * the subject who has symptoms of acute infection within a week. * Autoimmune diseases or Immune function defect, people has immunosuppressive therapy, cytotoxic treatment or inhaled corticosteroids in the past 6 months. * People has congenital malformations, developmental disorder or serious chronic diseases( such as Down's syndrome, diabetes, Sickle cell anemia or nerve system disease) * People has asthma Unstable that need emergency treatment, hospitalization, intubation, oral or intravenous corticosteroid in the past 2 years. * Diagnosed abnormal coagulation(Lack of clotting factors,Clotting disorders,Platelet abnormality) or significant bruising or coagulopathy * people has history or family history of convulsions, seizures, encephalopathy and psychiatric. * alienia, functional asplenia, and alienia or splenectomy in any situation. * Serious neurological disorders such as Green Barry syndrome. * people who has received blood products or immunoglobulin products in the past one months. * people who has received other study drug in the past one month. * people who received live attenuated vaccine, subunit vaccine or inactivated vaccine. * people who has received allergy treatment in in the past 14 days. * People who is on anti-TB treatment. * People whose axillary temperature is more than 37℃ before the vaccination. * People who is pregnant. * Any factors unsuitable for clinical trail according to the researchers.