TNF Polymorphism and Implantation Rate

Centre Hospitalier Universitaire de Nice120 enrolled

Overview

Do TNF-308 and -238 polymorphisms impact the embryo implantation rate after in vitro fertilization (IVF) in women without female infertility factor ?

This study was performed in order to verify whether TNF-308 allele was associated with a higher implantation rate and multiple pregnancy rates in women without known infertility factors after ovarian hyperstimulation with exogenous FSH for IVF

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Infertility

Interventions

biological and ultrasound testPROCEDURE

biological and ultrasound test 20 days after implantation in order to see the implantation rate

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 37 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Women * normal karyotype, * age under 38 years * serum follicle-stimulating hormone (Day-3 FSH) levels below 10 UI/l Exclusion Criteria: * age under 18 years

Locations (1)

Nice University Hospital

Nice, France

Outcomes

Primary Outcomes

Implantation rate by biological test

Time frame: 20 days after implantation

Implantation rate by ultrasound test

Time frame: 20 days after implantation

Data from ClinicalTrials.gov

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