Assessment of Exposures of the Mother-infant Pair to the Air Pollution of São Paulo

University of Sao Paulo General Hospital120 enrolled

Overview

A single group of pregnant women who was analyzed in the first and in the third trimesters of pregnancy

A single group of 120 pregnant women separated in smokers (n = 17) and nonsmokers (n = 103) and first pregnancy (n = 54) or multiparous (n = 66) who underwent pulmonary function test and used the individual passive sampler in the first and third trimesters of pregnancy

Study Type

INTERVENTIONAL

Allocation

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Enrollment

120

Conditions

Lung Diseases

Interventions

Lung function testPROCEDURE

Pregnant woman use the individual passive sampler 15 days before the spirometry test at each trimester

Eligibility

Sex: FEMALEMin age: 15 YearsMax age: 41 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * prior informed consent; * single pregnancy; * topical and feasible; * gestational age of less than 13.86 weeks at the first evaluation; * absence of preexisting maternal diseases Exclusion Criteria: * withdrawal from the project; * abortion; * inadequate pulmonary function test

Outcomes

Primary Outcomes

Effect of air pollution in the spirometry of 120 pregnants, evaluated by individual passive samplers in the first (T1) and third (T3) trimesters of pregnancy, using the non-parametric analysis for repeated measures

Time frame: Through study completion, an average of 3 year

Secondary Outcomes

Evaluation of the influence of smoking and parity and the results of spirometry of all pregnants exposed to pollution comparing the frequency of events held by Wilcoxon and the Mann Witney test

Time frame: Through study completion, an average of 3 year

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.