The aim of this phase 1 study is to determine the role of autologous adipose derived mesenchymal stem cells in the reduction of hemodialysis arteriovenous fistula failure when applied during the time of surgical creation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
74
A single topical application of mesenchymal stem cells derived from own fat biopsy to the surface of the outflow vein (right next to the fistula) over a five-minute period.
5-mL of Lactated Ringers solution topical application to the surface of the outflow vein (right next to the fistula) over a five-minute period.
Two topical applications of mesenchymal stem cells derived from own fat biopsy to the surface of the outflow vein (right next to the fistula) over a five-minute period at stage one and two of fistula surgery
Mayo Clinic in Rochester
Rochester, Minnesota, United States
Hemodialysis outflow vein diameter
Diameter of outflow vein by ultrasound
Time frame: Baseline to 12 months after AVF creation
Hemodialysis AVF Blood flow
blood flow by ultrasound or dialysis
Time frame: Baseline to 12 months after AVF creation
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.