Many patients receiving opioid based analgesia after spinal surgery experience postoperative nausea and vomiting (PONV) despite prophylaxis and treatment with antiemetic agents. Dehydration caused by fasting prior to surgery is associated with the development of PONV. The aim of this study is to investigate the effect of oral carbohydrates loading prior to surgery in patients at high risk of PONV undergoing spinal surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
288
oral carbohydrate beverage (12.8% carbohydrates, 50 kcal/100ml, 290 mOsm/kg, NO-NPO®, Daesang WelLife Co., Ltd., Korea) 400ml in the evening of the day before surgery and at 6 am on the day of surgery, respectively
NPO from midnight of the day before surgery
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine
Seoul, South Korea
RECRUITINGincidence of nausea and vomiting
Time frame: 48 hours
severity of nausea
11-point numerical rating scale (0: no nausea \~10: worst imaginable nausea)
Time frame: 48 hours
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