Mass Spectral Fingerprinting in Obstructive Sleep Apnoea

University of Zurich150 enrolled

Overview

To answer the question whether a previously detected breath profile in patients suffering from obstructive sleep apnoea (OSA) can be found in a cohort of patients with suspected OSA using mass spectrometry (validation study).

Study Type

OBSERVATIONAL

Enrollment

150

Conditions

Obstructive Sleep Apnoea (OSA)Exhaled Breath Mass Spectrometry

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical suspicion of obstructive sleep apnoea syndrome (based on clinical symptoms such as increased daytime sleepiness; Epworth Sleepiness Score (ESS) \> 10). * Age between 18 and 85 years at study entry. Exclusion Criteria: * None

Locations (1)

University Hospital Zurich, Division of Pneumology

Zurich, Canton of Zurich, Switzerland

Outcomes

Primary Outcomes

OSA-specific mass spectrometric pattern of VOCs in the exhaled breath

Concentration of volatile organic compounds (VOCs) in the exhaled breath will be analysed using mass spectrometry

Time frame: one hour, single measurement, no follow-up

Data from ClinicalTrials.gov

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