The Application of Spasmolytic in PCLE Examination of Superior Gastrointestinal Endoscope

Shandong University122 enrolled

Overview

Scopolamine butylbromide might be helpful for the outcome of superior gastrointestinal endoscope examination.

The peristalsis of gastrointestinal tract has a adverse affection on the process of the PCLE examination .Scopolamine butylbromide is a widely used spasmolytic，which can reduce the peristalsis of gastrointestinal tract effectly.The application of it may benefit the images'quality ,the acurrate of diagnosis and shorten the examination time.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

DOUBLE

Enrollment

122

Conditions

Using Copolamine Butylbromide in Probe-based Confocal Laser Endomicroscopy for Gastroendoscopy Examination

Interventions

Scopolamine HydrobromideDRUG

normal salineDRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * outpatients attending endomicroscopy * able to give written informed consent Exclusion Criteria: * coagulopathy * acute upper digestive tract bleeding * pregnancy or breast feeding * allergy to fluorescein sodium * impaired renal function

Locations (1)

Department of Gastroenterology, Qilu Hospital, Shandong University

Jinan, Shandong, China

Outcomes

Primary Outcomes

endomicroscopic image quality

Time frame: 7months

Data from ClinicalTrials.gov

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