Is the Decrease in the Bispectral Index Correlated With a Decrease in Cardiac Output During the Induction of Anaesthesia?

Centre Hospitalier Universitaire, Amiens45 enrolled

Overview

Monitoring the bispectral index (BIS) as a peri-operative hemodynamic tool appears to be justified by the agreement between various clinical situations in which BIS monitoring appears to be of value: the prognosis in traumatic head injury, the diagnosis of brain death , and the diagnosis of amniotic fluid embolism. The current controversy concerning the "triple low" state reinforces the need for an accurate study in this field. Furthermore, the recent review by Bidd argues in this sense.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Thoracic Surgery

Interventions

recording of cardiac outputDEVICE

other parametersDEVICE

BIS (bispectral index ), PI (perfusion index ), etCO2 (end-tidal carbon dioxide ), and brain NIRS (near-infrared spectroscopy)

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult (over-18) patients presenting an indication for general anaesthesia during elective cardiac surgery and being monitored for sedation depth * Good echogenicity * Social security coverage Exclusion Criteria: * Pregnancy * Subjects with black skin (a known technical limitation of plethysmography) * Cardiac arrhythmia * Sepsis * Poor echogenicity * Legal guardianship or incarceration * Complications of anaesthesia during induction (anaphylactic shock, cardiac arrest, arrhythmia, or intubation not possible)

Locations (1)

CHU Amiens

Amiens, France

Outcomes

Primary Outcomes

correlation between variations in the BIS and variations in cardiac output

as measured by transthoracic echocardiography

Time frame: Day 0

Secondary Outcomes

correlation between cardiac output and the perfusion index (PI) during the induction of anaesthesia.

measured by transthoracic echocardiography

Time frame: Day 0

correlation between cardiac output and end-tidal carbon dioxide (etCO2) during the induction of anaesthesia.

measured by transthoracic echocardiography

Time frame: Day 0

correlation between the cardiac output and the value of brain tissue oxygenation (measured by near-infrared spectroscopy (NIRS)) during the induction of anaesthesia

measured by transthoracic echocardiography

Time frame: Day 0

Data from ClinicalTrials.gov

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