This study compares mixed urinary incontinence symptoms before and after a combined treatment with Botox and Bulkamid. Eligible for the study are adult females with a mixed urinary incontinence, having both urgency urinary symptoms and stress urinary symptoms.
Study Type
OBSERVATIONAL
Enrollment
58
Intravesical injections of Botulinum toxin A (Botox) into the bladder wall.
Midurethral injections of the bulking Agent Bulkamid into the submucosal tissues of the urethra.
Cantonal Hospital Frauenfeld
Frauenfeld, Switzerland
Cure rates for stress urinary incontinence (SUI)
Number of participants with negative cough stress test and 90 % improved SUI-visual analog scale.
Time frame: 6 months
Change from baseline in number of micturitions per day
Time frame: Baseline, 6 months
Frequency of complications
Time frame: intra-operative and post-operative follow-up up to 12 months
Frequency of cough stress test levels
3 Levels: negative, only a few drops of urine, severe loss of urine
Time frame: Baseline, 6 months, 12 months
SUI-visual analog scale
Scale from 0-10: 0-no suffering - 10-severe suffering
Time frame: Baseline, 6 months, 12 months
UUI-visual analog scale
Scale from 0-10: 0-no suffering - 10-severe suffering
Time frame: Baseline, 6 months, 12 months
Change from baseline in number of micturitions per day
Time frame: Baseline, 6 months, 12 months
Change from baseline in number of urgency episodes per day
Time frame: Baseline, 6 months, 12 months
Change from baseline in number of urgency urinary incontinence episodes per 3 days
Time frame: Baseline, 6 months, 12 months
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Change from baseline in urine volume per micturition
Time frame: Baseline, 6 months, 12 months