The purpose of this research study is to see if pain can be better controlled with fewer side effects. The new drug regimen will study several different medicines that have different ways of treating pain.
The investigators plan to study an analgesic regimen of Ketamine and Lidocaine as infusions with Neurontin and acetaminophen delivered orally for postoperative analgesia and the subsequent effect on ventilator days and ICU stay. The investigators expect that pain scores will be either unchanged or better than historic controls. In addition, the investigators expect that ventilator days and ICU stay will be improved due to reduced incidence of delirium and bowel dysfunction.
Study Type
OBSERVATIONAL
Receive an analgesic regimen that involves Ketamine infusions
Receive an analgesic regimen that involves Lidocaine infusions
May be administered Acetaminophen rectally, by mouth, or intravenously in patients not suitable for either of the other methods of administration
Changes between the two groups assessed by overall ventilator days
Total ventilator days
Time frame: Through study completion, an average of one week
Changes between the two groups assessed by ICU length of stay
ICU length of stay
Time frame: Through study completion, an average of one week
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May be given Neurontin by mouth as an approved medication for pain control