Angiographic Characteristics of CSC, PCV Patients and Thrombotic Bio-markers

Samsung Medical Center100 enrolled

Overview

Thrombotic biomarkers and angiographic characteristics were compared among the de novo patients of central serous chorioretinopathy (CSC), polypoidal choroidal vasculopathy (PCV) and the control.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Central Serous Chorioretinopathy Polypoidal Choroidal Vasculopathy

Interventions

Blood samplingOTHER

Sampling the blood including DNA to investigate the thrombotic profile

Eligibility

Sex: ALLMin age: 20 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * CSC * neurosensory detachment in optical coherence tomography (OCT) * focal leakage in fluorescein angiography (FAG) and/or late choroidal hyperpermeability in indocyanine green angiography (ICGA) * PCV * subretinal and/or sub-retinal pigment epithelial fluid in OCT * branching vascular network and/or polyps in ICGA * Control * epiretinal membrane (ERM) * without underlying systemic, ophthalmic disease other than ERM Exclusion Criteria: * Previous history of using steroid (oral, topical) * Previous history of CSC/PCV * Previous history or evidence of intraocular inflammation including uveitis * Co-existing retinal or choroidal diseases * History of allergic reaction to fluorescein or indocyanine green dye * Underlying systemic conditions that could affect the thrombotic profiles (e.g. diabetes, hypertension, metabolic syndrome, coronary artery disease, cerebrovascular diseases, stroke, chronic renal failure, current smoker, pregnancy, sleep disorder)

Locations (1)

Samsung Medical Center

Seoul, South Korea

RECRUITING