Cognitive rehabilitation is defined as a systematic functionally oriented intervention of therapeutic cognitive activities based on the assessment and understanding of patient's brain behavior deficits. This project focuses on restoring cognitive functions in order to understand the underlying deficits in the patient's brain by developing integrated cognitive rehabilitation scenarios in virtual reality that combine memory, attention and problem solving training with context specific motor movements.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
59
Daily cognitive training with the Rehabilitation Gaming System (RGS) in the clinic during 6 weeks (5 days per week a 30 minutes).
Daily conventional cognitive rehabilitation at home as recommended by the neurologist during 6 weeks (5 days per week a 30 minutes).
Change in Digit Span Forward WAIS-IV from baseline to end of treatment and to follow-up
Measurement of attention
Time frame: Measured at baseline, at 6 weeks (end of treatment), and at 3-months (follow-up)
Change in Corsi block tapping test from baseline to end of treatment and to follow-up
Measurement of attention
Time frame: Measured at baseline, at 6 weeks (end of treatment), and at 3-months (follow-up)
Change in Trail Making Test, Part A from baseline to end of treatment and to follow-up
Measurement of attention
Time frame: Measured at baseline, at 6 weeks (end of treatment), and at 3-months (follow-up)
Change in Rey Auditory Verbal Learning Test from baseline to end of treatment and to follow-up
Measurement of episodic memory
Time frame: Measured at baseline, at 6 weeks (end of treatment), and at 3-months (follow-up)
Change in Digit Span Backward WAIS-IV from baseline to end of treatment and to follow-up
Measurement of working memory
Time frame: Measured at baseline, at 6 weeks (end of treatment), and at 3-months (follow-up)
Change in Corsi block-tapping test reversed from baseline to end of treatment and to follow-up
Measurement of working memory
Time frame: Measured at baseline, at 6 weeks (end of treatment), and at 3-months (follow-up)
Change in Frontal Assessment Battery from baseline to end of treatment and to follow-up
Measurement of executive functioning
Time frame: Measured at baseline, at 6 weeks (end of treatment), and at 3-months (follow-up)
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Change in Trail Making Test, Part B from baseline to end of treatment and to follow-up
Measurement of set-shifting
Time frame: Measured at baseline, at 6 weeks (end of treatment), and at 3-months (follow-up)
Change in Digit Symbol Coding in WAIS-IV from baseline to end of treatment and to follow-up
Measurement of processing speed
Time frame: Measured at baseline, at 6 weeks (end of treatment), and at 3-months (follow-up)
Change in Star Cancellation test from baseline to end of treatment and to follow-up
Measurement of spatial neglect
Time frame: Measured at baseline, at 6 weeks (end of treatment), and at 3-months (follow-up)
Change in Montreal Cognitive Assessment from baseline to end of treatment and to follow-up
Measurement of global cognitive ability
Time frame: Measured at baseline, at 6 weeks (end of treatment), and at 3-months (follow-up)
Change in Mini-Mental State Examination from baseline to end of treatment and to follow-up
Measurement of global health status
Time frame: Measured at baseline, at 6 weeks (end of treatment), and at 3-months (follow-up)
Change in Barthel Index from baseline to end of treatment and to follow-up
Measurement of independent functioning and mobility in activities of daily living
Time frame: Measured at baseline, at 6 weeks (end of treatment), and at 3-months (follow-up)
Change in Fugl-Meyer Assessment from baseline to end of treatment and to follow-up
Measurement of motor recovery after stroke
Time frame: Measured at baseline, at 6 weeks (end of treatment), and at 3-months (follow-up)