This study investigates the clinical and neural effects of stress management skill building programs for young adults with childhood adversity. The investigators will recruit a total of 60 young adults (21-35 years old) who will be randomized into two different stress management skill building programs, both of which are 8 weeks long. MRI and psychological assessments will be acquired from all subjects before and after the intervention programs in order to investigate changes in clinical symptoms (such as depression, anxiety and stress) and hippocampus structure and function as well as other neural changes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
73
Subject will meet with the instructor and other students in the group once a week and complete homework and track amount of practice during the week.
Subject will meet with the instructor and other students in the group once a week and complete homework and track amount of practice during the week.
McLean Hospital
Belmont, Massachusetts, United States
Changes in hippocampal subfield gray matter density measured with high resolution structural MRI at 3T
Time frame: before and after the 8-week intervention
Changes in stress level measured by the Perceived Stress Scale (PSS)
Time frame: before and after the 8-week intervention
Changes in severity of depression symptom measured by Beck Depression Inventory (BDI)
Time frame: before and after the 8-week intervention
Changes in severity of anxiety symptom measured by State-Trait Anxiety Inventory (STAI)
Time frame: before and after the 8-week intervention
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