The purpose of the study it to compare the effects of Holy-Comod and Tears Naturale Forte on ocular surface and tear inflammatory mediators in patients after Phaco+IOL.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
80
The patients were administrated Hylo-Comod eye drop four times a day after Phaco+IOL
The patients were administrated Tears Naturale Forte eye drop four times a day after Phaco+IOL
Hainan Eye Hospital, Zhongshan Ophthalmic Center of Sun Yat-sen University
Haikou, Hainan, China
RECRUITINGscale of Schirmer I test
Time frame: up to 2 months after surgery
scale of corneal fluorescein staining
Time frame: up to 2 months after surgery
scale of noninvasive tear breakup time
Time frame: up to 2 months after surgery
questionnaire of ocular surface disease index
Time frame: up to 2 months after surgery
scale of central corneal sensitivity
Time frame: up to 2 months after surgery
scale of tear meniscus height
Time frame: up to 2 months after surgery
concentration of Interleukin-1α
Time frame: up to 2 months after surgery
concentration of tumor necrosis factor-α
Time frame: up to 2 months after surgery
concentration of nerve growth factor
Time frame: up to 2 months after surgery
concentration of interferon-γ
Time frame: up to 2 months after surgery
concentration of transforming growth factor-β1
Time frame: up to 2 months after surgery
concentration of matrix metalloproteinase-9
Time frame: up to 2 months after surgery
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Correlation Between Inflammatory Mediators and Ocular Surface Changes
Time frame: up to 2 months after surgery