Impact of Physical Activity on Patients With Chronic Kidney Disease Not Receiving Dialysis Followed in the TIRCEL Network. An Exposed / Unexposed Study (PHYSALYS)

Hospices Civils de Lyon259 enrolled

Overview

PHYSALYS is an observational multicenter study. It's an analytical study comparing 2 groups: patients exposed to physical activity and unexposed. The main objective of the study is to compare the evolution of glomerular filtration rate at inclusion and 12 months later between patients practicing physical activity and patients not practicing. If necessary, the renal disease-related complications, which are not influenced by physical activity: (type of kidney disease, age and tobacco), would be taken into account. TIRCEL patients with chronic kidney disease (CKD) at stages 3, 4 or 5 can be included in the study. Their serum creatinine data, 12 months prior to inclusion, is collected retrospectively. Patients are followed in the trial during 12 months. To evaluate physical activity, patients respond to Global Physical Activity Questionnaire 2 (GPAQ2) at inclusion and 12 months later. During this 12 months period, the same biological data are collected prospectively.

Study Type

OBSERVATIONAL

Enrollment

259

Conditions

Renal Insufficiency, Chronic

Interventions

Global Physical Activity QuestionnaireOTHER

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Members of TIRCEL (Traitement de l'Insuffisance Chronique en rhônE-aLpes) network for over a year and having at least two measurements of glomerular filtration rate with an interval of 9 to 12 months between the first and the last measurement * Patients in stages 3, 4 or 5 of CKD * No dialysis CKD patients * Non transplanted CKD patients * Patients seeing nephrologist * Patients agreeing to be contacted for a phone call half an hour * Adults patients (\> 18 years) * Patients not living in institution * Patients being able to answer a questionnaire Exclusion Criteria: * Patients followed in the TIRCEL (Traitement de l'Insuffisance Chronique en rhônE-aLpes) network for less than one year or having less than 2 measurements of glomerular filtration rate with an interval of least 9 months or over 12 months between the first and the last measurement * Patients in stages 1 or 2 of CKD * CKD patients receiving dialysis * Transplanted CKD patients * Patients not seeing nephrologist * Patients refusing to be contacted for a phone call half an hour * Patients \< 18 years * Patients living in institution * Patients unable to answer a questionnaire

Outcomes

Primary Outcomes

Change of the Glomerular Filtration Rate (GFR)

The Glomerular Filtration Rate (GFR) annual slope between inclusion (M0) and 12 months (M12) after inclusion in exposed and unexposed groups.

Time frame: Month 0, Month 12