Benefit of a Diagnostic MRI in Case of Pathological Nipple Discharge With Normal Mammography / Ultrasound

N/ACompletedNCT02819362

Institut Bergonié70 enrolled

Overview

Benefit of MRI in pathological nipple discharge.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Breast Cancer

Interventions

MRIDEVICE

The magnetic resonance imaging (MRI) will be performed before the two-step surgery: a ductal-MRI sequence (highly weighted sagittal T2) - followed by sequence with axial plane, T2, T1, injection in dynamic sequences, subtractions.

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Single pore nipple discharge neither green nor milky. 2. Mammography (at least 2 shots, +/- centred on retro-areal) normal. 3. Initial ultrasound: normal. 4. Age over 18 years 5. Female 6. Patient affiliated to the social security scheme. 7. Patient information and informed consent signed and dated Exclusion Criteria: Physiological milky or green discharge

Locations (1)

Institut Bergonié

Bordeaux, France

Outcomes

Primary Outcomes

The Negative Predictive Value (PVV) of MRI

The negative predictive value (NPV) of MRI in patients with pathological nipple discharge with normal mammography / ultrasound. The VPN is defined by the ratio: number of patients with a normal histological examination / number of patients with a normal MRI.

Time frame: At baseline

Data from ClinicalTrials.gov

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