Post-marketing Surveillance (Special Use-results Surveillance) on Long-term Use With Ryzodeg®

Inclusion Criteria: * Signed consent obtained before any study-related activities (study-related activities are any procedure related to recording of data according to the protocol) * The decision to initiate treatment with commercially available Ryzodeg® has been made by the patient/Legally Acceptable Representative (LAR) and the treating physician before and independently from the decision to include the patient in this study * Patients with diabetes mellitus requiring insulin therapy for whom the physician has decided to start treatment with Ryzodeg® * Male or female, no age limitation Exclusion Criteria: * Patients who are or have previously been treated with Ryzodeg® * Previous participation in this study. Participation is defined as having given informed consent in this study * Patients with a history of hypersensitivity to study product components * Mental incapacity, unwillingness or language barriers precluding adequate understanding or cooperation