Effectivity and Safety of Ultrasound-guided Percutaneously Laser Ablation for Refractory Neoplasms

Phase 2UnknownNCT02822053

First Affiliated Hospital of Zhejiang University100 enrolled

Overview

The purpose of this study is to evaluate the safety and efficacy of ultrasonography (US) -guided laser ablation liver, kidney, pancreas, lung and retroperitoneal tumors, the investigators used preoperative and postoperative US/CEUS/CT/MRI to assess lesions, and laboratory tests including the tumor markers to evaluate the general condition of patients. Intraoperative US/CEUS/CT would be applied to monitor ablation lesions.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

100

Conditions

Refractory Neoplasms

Interventions

US-guided laser ablation for refractory neoplasmsPROCEDURE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with small hepatocellular carcinoma (single or multiple nodules of less than 3 cm in diameter), * Patients with Child-Pugh A/B, * Patients with PLT ≥ 50\*10E9/L and PT ≤ 20s. Exclusion Criteria: * Patients with blood coagulation dysfunction, ChildPugh ≥3, severe cardiopulmonary disease, intolerant anesthesia and upper gastrointestinal bleeding in shock.

Locations (1)

The First Affiliated Hospital of Zhejiang University

Hangzhou, Zhejiang, China

RECRUITING

Outcomes

Primary Outcomes

100 patients of refractory neoplasms with image-guided laser ablation-related effectivity as assessed by MRI

Time frame: up to 24 months

Central Contacts

Tian'an Jiang, Phd

CONTACT

+86 18857127666 tiananjiang@126.com

Guo Tian, Master

CONTACT

+86 13600529967 871035504@qq.com

Data from ClinicalTrials.gov

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