Clinical and Genetic Factors on the Postoperative Recovery Time of General Anaesthesia

Yijing He1,453 enrolled

Overview

To evaluate the effect of clinical factors on the recovery time of postoperative anesthesia and the effect of genetic variation in gDNA on the recovery time of postoperative anesthesia.

Recovery time of postoperative anesthesia is an important index to reflect patient's postoperative health status. The investigators want to collect patients' clinical dates and their blood samples, then extract DNA from blood samples, acquire every patients' genetic variation information. Finally, acquiring the mathematical model of the influence of clinical factors and genetic factors on the recovery time after operation, predicting the recovery time of anesthesia.

Study Type

OBSERVATIONAL

Enrollment

1,453

Conditions

General Anesthesia

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Aged more than 18 years; 2. General anesthesia for all patients; 3. Patients underwent surgery for laparoscopic surgery, orthopedics surgery or open surgery; 4. Patients were not delivered allogeneic blood in three months; 5. Having the ability to understand and sign the informed consent. Exclusion Criteria: 1. Pregnant or lactating women; 2. Having an immune deficiency, as a patient with HIV infection; 3. Patients with infectious diseases, such as syphilis; 4. Patients delivered allogeneic blood in three months; 5. Researchers believe that may increasing the risk of subjects or interfering clinical trial; 6. Don't have the ability to understand or sign the informed consent.

Locations (1)

Xiangya Hospital Central South University

Changsha, Hunan, China

Outcomes

Primary Outcomes

Recover time of anesthesia

Time frame: within 24 hours

Data from ClinicalTrials.gov

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