This study will collect data from multiple academic institutions. The primary objective for part A of this study is to determine the impact of anesthetic injection rate and temperature on pain perception during dermatologic procedures, and the objective for the part B of this study is to determine if buffering of the anesthetic solution alters pain perception. This study is a pilot study designed to determine feasibility of these procedures.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Enrollment
26
The room temperature local anesthetic agent will be administered by slow infiltration.
The room temperature local anesthetic agent will be administered by rapid infiltration.
The warmed local anesthetic agent will be administered by slow infiltration.
Northwestern University Department of Dermatology
Chicago, Illinois, United States
Pain on a Visual Analog Scale (VAS)
Subjects will rate the pain VAS score immediately after the needle is withdrawn. They will be asked to rate the pain of the injection of the solution. VAS pain scale is rated on a 10 cm scale with 0 cm being no pain and 10 cm being extremely painful.
Time frame: intraoperative
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The warmed local anesthetic agent will be administered by rapid infiltration.
One side of the body will be randomized to receive an injection of the buffered agent, while the contralateral side will be assigned to receive an injection of the unbuffered anesthetic agent.
One side of the body will be randomized to receive an injection of the buffered agent, while the contralateral side will be assigned to receive an injection of the unbuffered anesthetic agent.
Injectable lidocaine solution (Lidocaine Hydrochloride and Epinephrine)
Sodium Bicarbonate