Pancreas Volume and Diabetes Status Following Pancreatectomy

Florida Hospital Tampa Bay Division100 enrolled

Overview

This study will enroll 100 patients scheduled to undergo a pancreatectomy. The primary objective is to develop a scoring system using pancreatic volume measured by CT scan and intraoperative measurements of the pancreas parenchyma to predict the onset of diabetes mellitus after a pancreatectomy. The investigators will also monitor patients with pre-existing diabetes to see if their diabetes worsens or improves.

The primary objective is to develop a scoring system using pancreatic volume measured by CT scan and intraoperative measurements of the pancreas parenchyma to predict the onset of diabetes mellitus after a pancreatectomy. The investigators will also monitor patients with pre-existing diabetes to see if their diabetes worsens or improves. Patients will be followed up to one year to track their diabetes status, postoperative outcomes and quality of life.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Pancreatic Neoplasms

Interventions

PancreatectomyPROCEDURE

Patients will undergo pancreatectomy as part of routine care for their pancreatic neoplasms.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All patients undergoing pancreatectomy at our institution (e.g., pancreaticoduodenectomy, distal pancreatectomy, distal pancreatectomy and splenectomy, central pancreatectomy). Exclusion Criteria: * All patients who are on steroids or other medications whose potential side effects include development of diabetes mellitus or elevated blood glucose. * Pregnant or nursing women. * Patients with uncontrolled diabetes (HbA1c \>8%).

Outcomes

Primary Outcomes

Percent resected volume of pancreas and diabetes development

Time frame: Postoperative up to one year

Secondary Outcomes

QLQ-C30 Quality of Life Health Questionnaire

Time frame: Postoperative up to one year

Blood glucose control

Time frame: Postoperative up to one year

Data from ClinicalTrials.gov

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