Psychosocial Risk Factors in Stroke and Myocardial Infarction

Centre Hospitalier Universitaire Dijon294 enrolled

Overview

The aim of this study is to identify groups of subjects at risk of recurrence in secondary prevention based on Psychosocial Factors. The aim is also to propose novel levers to reduce health inequalities in this population so as to develop new prevention strategies for neuro- and cardio-vascular health This study is based on data from questionnaires (Quality of life at work, perceived stress, perceived disease severity) and on behavior indicators (factors related to lifestyle: alcohol, smoking, obesity, sedentarity). Biomarkers of endothelial function (ADMA) will also be assayed. It's an interventional study because of blood sample

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

294

Conditions

Myocardial Infarction Stroke

Interventions

Eligibility

Sex: ALLMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who have provided oral consent to participate * Patients over 18 years * Patients hospitalized for type 1 MI or ischemic stroke/TIA \< 24H after symptom onset * Age \< 65 years * With a professional activity (INSEE definition) at the time of the neuro or cardiovascular event * At least one of the following risk factors: current smoking, obesity (waist circumference \> 88 cm (W)/102 cm (M) or a waist/hip ratio 0.85(W)/0.9(M), sedentarity (physical activity \< 150 min / week), alcohol consumption (\> 3 standard glasses per day for men, \> 2 standard glasses/d for women) Exclusion Criteria: * Adult under guardianship * Patients without national health insurance cover * Pregnant or breast-feeding women * Clinical state making it impossible to use questionnaires or to measure risk factors * Stroke or TIA not related to atheroma or cardioembolism (dissection, hemopathy…) * type \> 1 MI

Outcomes

Primary Outcomes

number of psychosocial factors (PSF) on the level of risk for neuro-cardiovascular disease.

Time frame: through the completion study an average of 6 month

Secondary Outcomes

study the proportion of diméthyl-arginine asymetrical (ADMA) in patients with PSF

Time frame: 1st day