Comparison of two techniques of renal pre-transplant infusion on the evolution of renal function in the recipient: multicentre randomized trial
Both machines differ in their operation: the LifePort® machine manufactured by the "Organ Recovery System (ORS)," says renal perfusion by maintaining a continuous perfusion pressure that is adjustable, while the Waves machine company "Medical Waters" assures infusion maintaining a controlled pulsatile flow. Both machines are now available but the investigators currently have no study of whether an infusion type is superior to the other in terms of results on renal function recipients. Study the impact of both types of infusion on renal function recipients evaluated in the early days of transplantation, at three months and one year after the transplant.
Study Type
OBSERVATIONAL
Enrollment
228
Renal Perfusion with LifePort® perfusion device
Renal Perfusion with Waves perfusion device
Coordination Hospitalière de PMO , Pôle USSAR-Anestéthésie -Réa CHU-ANGERS
Angers, France
Coordination Hospitalière de PMO-Anestésiste -réanimateur, CHU-Bordeaux -GROUPE HOSPITALIER PELLEGRIN DAR I
Bordeaux, France
CHD-Vendée-Les Oudairies
La Roche-sur-Yon, France
Glomerular Filtration Rate
Rate of patients with a Glomerular Filtration Rate (GFR) calculated by the MDRD ≥ 45 ml / min / 1,73m² (considered normal in a renal graft) at 3 months post-transplantation (MDRD: Modification of Diet in Renal the Disease)
Time frame: 3 months
Creatinine <250 mg / dL
Time for obtaining a serum creatinine \<250 mg / dL and need for dialysis in recovery during the first seven days post transplant.
Time frame: 1 week
RFG
Absence of a recovery renal function at 1 month.
Time frame: 1 month
MDRD
Modification of Diet in Renal the Disease at 1 year
Time frame: 1 year
GSR
graft survival rate at 1 year.
Time frame: 1 year
Renal Biopsie results
Results of analyzes of kidney biopsies punctures to 3 months.
Time frame: 3 months
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Coordination des prélèvements d'organes et de Tissus- CHU-Limoges -CHU- DUPUYTREN
Limoges, France
Chirurgien-Chirurgie de la transplantation et d'Urologie, Pavillon V, Hôpital Edouard HERRIOT
Lyon, France
Coordination des prélèvements d'organes et de Tissus,CHU-NANTES
Nantes, France
Coordination des prélèvements d'organes et de Tissus Pôle Anesthésie-Réanimations,University Hospital
Tours, France