Effect of Intravenous Magnesium on Postoperative Sore Throat After Thyroidectomy

Ajou University School of Medicine20 enrolled

Overview

The primary purpose of this study is to investigate the effect of intravenous magnesium on postoperative throat pain after thyroidectomy. The secondary purpose of this study is to investigate the effect of intravenous magnesium on total dose of fentanyl in recovery room after thyroidectomy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Thyroid Neoplasms

Interventions

Magnesium SulfateDRUG

adminstration of intravenous magnesium as bolus of 50 mg/kg, followed by continuous infusion at rate of 10 mg/kg/h

Normal salineDRUG

the same bolus and infusion volumes of normal saline

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Thyroidectomy Exclusion Criteria: * Allergy to magnesium * Chronic pain * Chronic opioid use * Chronic NSAID use * Renal dysfunction * Liver dysfunction * Cardiac arrythmia * Seizure

Locations (1)

Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine

Suwon, Seoum, South Korea

Outcomes

Primary Outcomes

Throat pain

pain assessment using visual analog scale

Time frame: Up to 48 hours after surgery end

Secondary Outcomes

Fentanyl dose in recovery room

Time frame: Up to 30 minutes after surgery end

Data from ClinicalTrials.gov

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