Study to Evaluate Safety, Tolerability, and Immunogenicity of Candidate Human Cytomegalovirus Vaccine in Healthy Adults

Inclusion Criteria: 1. Generally healthy adult female and male 18 to 40 years of age, inclusive; 2. Serologically confirmed to be CMV seronegative at screening; 3. Female volunteers must agree to use an adequate contraception method as deemed appropriate by the investigator 4. Sign an informed consent document indicating understanding of the purpose and procedures required for the study and willingness to participate in the study Exclusion Criteria: 1. History of or current clinically significant medical illness or any other illness that in the opinion of the investigator interferes with the interpretation of the study results 2. Clinically significant abnormal physical examination, vital signs, or clinically significant abnormal values for hematology, clinical chemistry or urinalysis at screening as determined by the investigator 3. Previous receipt of any cytomegalovirus vaccine 4. History of allergic reactions or anaphylactic reaction to any vaccine component 5. Pregnant or breastfeeding or plans to conceive from two weeks before the study start through six months after the last dose of study vaccine 6. Known or suspected impairment of immunological function, including but not limited to autoimmune diseases, splenectomy, or HIV/AIDS 7. Chronic administration (defined as more than 14 days in total) of immune-suppressive or other immune-modifying drug with six months prior to the product dose (for corticosteroids, this is defined as prednisone ≥20 mg/day or equivalent). Inhaled and topical steroids are allowed 8. Participation in another clinical study within 30 days or plans to participate in another treatment based clinical study during the conduct of the present study 9. Any skin abnormality or tattoo that would limit post-vaccination injection site assessment 10. Any history of cancer requiring chemotherapy or radiation within 5 years of randomization or current disease 11. Are family members of study center staff