Evaluation of Novel Lung Function Parameters in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Universitätsmedizin Mannheim150 enrolled

Overview

Current guideline-based criteria defining COPD do not meet the challenges set by the complex pathophysiology of the disease. The investigators therefore aimed to evaluate novel or not widely used diagnostic approaches for the detection and therapeutic monitoring of COPD.

Study Type

OBSERVATIONAL

Enrollment

150

Conditions

COPD Obstructive Ventilation Disorder Pulmonary Emphysema

Interventions

impulse oscillometryDEVICE

multiple breath washout testDEVICE

body plethysmographyDEVICE

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * known or suspected COPD * known or suspected obstructive ventilation disorder * pulmonary healthy controls Exclusion Criteria: * pregnancy * inability to participate

Locations (1)

University Medical Center Mannheim

Mannheim, Germany

RECRUITING

Outcomes

Primary Outcomes

lung clearance index (LCI) as determined by multiple breath washout

Time frame: 30 minutes

airway resistance and reactance (R5, X5, R-D5-20) as determined by impulse oscillometry

Time frame: 30 minutes

Secondary Outcomes

repeatability of lung clearance index (LCI)

Time frame: 30 minutes

Central Contacts

Frederik Trinkmann, Dr.

CONTACT

+496213833879 frederik.trinkmann@umm.de

Data from ClinicalTrials.gov

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