Evaluation of Novel Lung Function Parameters in Patients With Interstitial Lung Disease (ILD)

Universitätsmedizin Mannheim50 enrolled

Overview

Current diagnostic tools used in interstitial lung disease (ILD) do not meet the challenges set by the complex pathophysiology of this heterogenous group. The investigators therefore aimed to evaluate novel or not widely used diagnostic approaches for the detection and therapeutic monitoring of patients with various ILDs.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Pulmonary Healthy Controls Interstitial Lung Disease Idiopathic Pulmonary Fibrosis Non-specific Interstitial Pneumonia Sarcoidosis Granulomatosis With Polyangiitis (Wegener's Disease)

Interventions

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * known or suspected interstitial lung disease Exclusion Criteria: * pregnancy * inability to participate

Outcomes

Primary Outcomes

lung clearance index (LCI) as determined by multiple breath washout

Time frame: 30 minutes

airway resistance and reactance (R5, X5, R-D5-20) as determined by impulse oscillometry

Time frame: 30 minutes

Secondary Outcomes

repeatability of lung clearance index (LCI)

Time frame: 30 minutes

Data from ClinicalTrials.gov

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Evaluation of Novel Lung Function Parameters in Patients With Interstitial Lung Disease (ILD)

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Secondary Outcomes

Central Contacts