Feasibility Study of Phase-contrast MRI for Flow in the External Carotid Branches Arteries

Centre Hospitalier Universitaire, Amiens80 enrolled

Overview

The phase-contrast MRI offers the advantage to combine precisely vascular flow measurements data with morphological images. Even if the anatomy of the external carotid artery is well known, data obtained through Phase contrast MRI could permit to progress in several fields of cranio-maxillofacial surgery as for example arteriovenous malformations,radionecrosis, head and neck micro-reconstructive surgery. The aim of this study is to establish and develop Phase-contrast MRI sequences for vascular flow characterization branches of the external carotid artery in healthy patients and in pathological cases.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Carotid Artery, External

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * group 1 : healthy volunteer * group 2 : X-Ray treatment antecedent (at least 50 grays and older than one year) * group 3 : antecedent of embolization of branches of external carotid artery * group 4 : antecedent of muscular free flap surgery (older than one month) * free and informed consent Exclusion Criteria: * group 1 : facial pathology, antecedent of facial injury, antecedent of X-Ray treatment in head and neck localisation, antecedent of head and neck cancer * group 2 : antecedent of surgery for head and neck cancer or for vascular disease * group 3 : antecedent of surgery for head and neck cancer or for vascular disease ; antecedent of X-Ray treatment. * group 4 : antecedent of surgery for head and neck cancer or for vascular disease ; antecedent of X-Ray treatment or embolization * patient with guardianship or trusteeship * MRI cons-indications * pregnancy and lactation

Outcomes

Primary Outcomes

measurability of flow 1

flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the maximum speed

Time frame: 1 hour

measurability of flow 2

flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the minimum speed

Time frame: 1 hour

measurability of flow 3

flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the average speed

Time frame: 1 hour

measurability of flow 4

flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the maximum flow rates

Time frame: 1 hour

measurability of flow 5

flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the minimal flow rates

Time frame: 1 hour

measurability of flow 6

flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the medium flow rates

Time frame: 1 hour

Feasibility Study of Phase-contrast MRI for Flow in the External Carotid Branches Arteries

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Central Contacts