Graft-versus-host Disease Associated Myelosuppression

Technische Universität Dresden50 enrolled

Overview

The objective is to measure the frequency, functionality and phenotype of bone marrow-derived mesenchymal stromal cells in patients after allogeneic hematopoietic stem cell transplantation. Furthermore, the immune cell infiltrate of the bone marrow will be monitored at the same time. These results will be correlated with the extent of cytopenia and clinical graft-versus-host disease grading.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Abnormal Hematopoiesis Allogenic Disease Graft vs Host Disease

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * age \>18 * acute myeloid leukemia * myelodysplastic syndrome * hematopoietic stem cell transplantation Exclusion Criteria: * not willing to take part

Locations (1)

Medizinische Klinik und Poliklinik I, Universitätsklinikum, TU Dresden

Dresden, Germany

RECRUITING

Outcomes

Primary Outcomes

Changes in the amount of mesenchymal stromal cells after allogeneic hematopoietic stem cell transplantation

Time frame: up to 1 year after allogeneic hematopoietic stem cell transplantation

Central Contacts

Malte von Bonin, MD

CONTACT

00493514586636 malte.bonin@uniklinikum-dresden.de

Data from ClinicalTrials.gov

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