Evaluation of the Clinical, Neuropsychological and Psychosocial Situation of Patient With Eating Disorders.

University Hospital, Montpellier370 enrolled

Overview

Eating disorders (ED) are serious mental illnesses with an excess mortality and many affects in the quality of life of patients and thier relatives. Management of ED is very difficult : the prognosis remains relatively poor both in terms of remission rate and quality of life. In this context, the contribution of new strategies for pathophysiological exploration and the development of therapeutic options are crucial. In this project the investigators aim to constitute un cohort of patients from a day unit specialized in the management of ED. A prospective follow-up will be offered to patients to assess their clinical and psycho-social evolution. The overall objective is to identify which factors are prognostic of clinical improvement of the ED. We also want to better characterize patients that will migrate from diagnosis to another.

The investigators propose to assess, with a cohort of patients with ED the prognostic value of cognitive abnormalities associated with ED (cognitive flexibility and central coherence) They will recruit 370 patients suffering from a current ED (anorexia, bulimia, binge eating disorder, Eating disorder not otherwise specified). Each patient will be reassessed every year for 3 years.

Study Type

INTERVENTIONAL

Allocation

Masking

NONE

Enrollment

370

Conditions

Eating Disorders

Interventions

Eligibility

Sex: ALLMin age: 15 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion criteria: * respond to DSM 4 criteria for ED * Age 15 to 65 years * Signing an informed consent. * Affiliated to a social security scheme or being the beneficiary of such a scheme. Exclusion criteria: * Manifest inability of the subject to understand / perform clinical and neuropsychological evaluations and tasks * Major protected by law (guardianship) * Privation of liberty by judicial or administrative decision * Pregnant or lactating women

Outcomes

Primary Outcomes

Frequency of remission rates

study of remission rates frequency at 12 months depending on the Brixton score assessed at baseline (assessment of cognitive flexibility). Remission is defined as disappearance of ED Diagnostic and Statistical Manual (DSM) criteria.

Time frame: At the inclusion and at 12, 24 and 36 months

Secondary Outcomes

score to another neuropsychological test (Iowa gambling task (IGT)

Study of remission rates frequency at 12 months depending on the IGT score (decision making) assessed at baseline

Time frame: At the inclusion and at 12, 24 and 36 months

scores to another other neuropsychological test : Rey-Osterrieth complex figure

Study of remission rates frequency at 12 months depending on the Rey figure assessed at baseline

Time frame: At the inclusion and at 12, 24 and 36 months

scores to another neuropsychological test : D2 test of attention

Study of remission rates frequency at 12 months depending on the D2 test (attention) assessed at baseline

Time frame: At the inclusion and at 12, 24 and 36 months