Study Comparing the Role of the Laparoscopy Surgical Staging in the Peritoneal Carcinomatosis to Laparotomic Approach

Hospices Civils de Lyon50 enrolled

Overview

The peritoneum is the second most common site of recurrence in patients with colorectal cancer. Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy improve the prognosis of these patients and incorporates surgical removal of all visible disease followed by chemical destruction of microscopic disease through chemoperfusion. The most validated predictors of outcome are preoperative tumor burden measured in terms of the peritoneal carcinomatosis index (PCI) and completeness of cytoreduction (CC score). Diagnostic laparoscopy prior to resection is widely used in hepatopancreaticobiliary and colorectal cancer and has been shown to be effective in excluding unnecessary laparotomy associated with higher morbidity.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Colorectal Peritoneal Carcinomatosis

Interventions

Non interventionalOTHER

Peroperative data collection

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with Colorectal cancer with a resected minimal synchronous peritoneal carcinomatosis, or ovarian metastases, tumour rupture in the abdominal cavity. * Patients received six months of systemic chemotherapy (currently the Folfox-4 regimen which could be modified if the standard is modified) Exclusion Criteria: * None

Locations (1)

Hospices Civils de Lyon - Centre Hospitalier Lyon Sud Service de Chirurgie Générale et Digestive - 165 chemin du grand Revoyet

Pierre-Bénite, France

RECRUITING

Outcomes

Primary Outcomes

Peritoneal carcinomatosis staging

To score the Collect detailed detailed Peritoneal Cancer Index (PCI) by laparoscopy following the laparotomy procedure in order to evaluate the accuracy and adequacy of laparoscopic surgical staging comparing to laparotomic approach.

Time frame: during laparoscopy and during laparotomy (Day 1)