The purpose of this study is to determine if the infusion of the local anesthetic ropivacaine (a numbing medicine) and the non-steroidal anti-inflammatory drug ketorolac (a pain killer similar to ibuprofen) through a catheter placed along the cesarean delivery incision, will reduce the pain experienced after cesarean section and need for narcotic pain medicine.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
84
Duke University Hospital
Durham, North Carolina, United States
Pain Score on Movement (Sitting in Bed From a Supine Position)
Score reported on a scale of 0-10, with 0 being none and 10 being the worst imaginable
Time frame: 24 hours after surgery
Pain Scores at Rest
Score reported on a scale of 0-10, with 0 being none and 10 being the worst imaginable
Time frame: 2 hours
Pain Scores at Rest
Score reported on a scale of 0-10, with 0 being none and 10 being the worst imaginable
Time frame: 24 hours
Pain Scores at Rest
Score reported on a scale of 0-10, with 0 being none and 10 being the worst imaginable
Time frame: 48 hours
Opioid Consumption
measured in mg oxycodone equivalents
Time frame: 2 hours
Opioid Consumption
measured in mg oxycodone equivalents
Time frame: 24 hours
Opioid Consumption
measured in mg oxycodone equivalents
Time frame: 48 hours
Time to First Rescue Analgesic
Time frame: 48 hours
Number of Subjects Experiencing Nausea
Asking patients whether or not they experienced the symptom in the preceding time-frame
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Time frame: 2 hours
Number of Subjects Experiencing Nausea
Asking patients whether or not they experienced the symptom in the preceding time-frame
Time frame: 24 hours
Number of Subjects Experiencing Nausea
Asking patients whether or not they experienced the symptom in the preceding time-frame
Time frame: 48 hours
Number of Subjects Experiencing Vomiting
Asking patients whether or not they experienced the symptom in the preceding time-frame
Time frame: 2 hours
Number of Subjects Experiencing Vomiting
Asking patients whether or not they experienced the symptom in the preceding time-frame
Time frame: 24 hours
Number of Subjects Experiencing Vomiting
Asking patients whether or not they experienced the symptom in the preceding time-frame
Time frame: 48 hours
Number of Subjects Experiencing Pruritus
Score reported on a scale of 0-10, with 0 being none and 10 being the worst imaginable
Time frame: 2 hours
Number of Subjects Experiencing Pruritus
Score reported on a scale of 0-10, with 0 being none and 10 being the worst imaginable
Time frame: 24 hours
Number of Subjects Experiencing Pruritus
Score reported on a scale of 0-10, with 0 being none and 10 being the worst imaginable
Time frame: 48 hours
Patient Satisfaction With Postoperative Analgesia on a 0-10 Scale
Score reported on a scale of 0-10, with 0 being not at all satisfied and 10 being completely satisfied
Time frame: 48 hours
Number of Subjects With Chronic Pain
Phone interview asking patient about presence of pain at incision site
Time frame: 8 weeks
Number of Subjects With Chronic Pain
Phone interview asking patient about presence of pain at incision site
Time frame: 6 months
Postpartum Depression, as Measured by the Edinburgh Postnatal Depression Scale
Patients contacted over the phone completed screening with the EPDS, on a scale of 0-30. A score of over 13 indicate risk for postpartum depression
Time frame: 8 weeks
Postpartum Depression, as Measured by the Edinburgh Postnatal Depression Scale
Patients contacted over the phone completed screening with the EPDS, on a scale of 0-30. A score of over 13 indicate risk for postpartum depression
Time frame: 6 months
Pain Score on Movement
Score reported on a scale of 0-10, with 0 being none and 10 being the worst imaginable
Time frame: 48 hours after surgery