Abdominal pain disorders functional (including functional dyspepsia, irritable bowel syndrome, abdominal migraine, functional abdominal pain) is a very common disease in the pediatric population, where classical medical treatment does not always prove effective. This clinical entity has an impact on the individual physiological balance particularly on the autonomic regulation. Studies concerning adults with irritable bowel syndrome, showed significant changes in heart rate variability indices (HRV: heart rate variability). The study of time and frequency domain analysis of HRV allows noninvasive and reproducible assessment of the cardiac sympathetic and parasympathetic tone. The investigators hypothesize that the sympathovagal balance could be altered in children in case of prolonged nociceptive stress as the investigators find it especially in irritable bowel syndrome and functional abdominal pain. In recent years, the control of pediatric pain experienced considerable growth through hypnosis techniques and several studies have shown analgesic efficacy with a beneficial effect in terms of quality of life in children. Our study aims to assess the impact of the hypno-analgesia treatment of Abdominal pain disorders functional on sympathovagal balance. The investigators propose to realize in 7 to 18 years old children with Abdominal pain disorders functional a single center prospective study to highlight after a standardized hypnosis program, changes in the time and frequency domain indices of heart rate variability and clinical or quality of life parameters. The primary endpoint will be the high frequency HF indice. Secondary endpoints will be the other indices of HRV (Ptot, VLF, LF, ratio LF / HF, SDNN, SDANN, pNN50, RMSSD), the Quality of Life Questionnaire values (PedsQL ™ 4.0) a pain scale and the composite score of Francis.
Study Type
OBSERVATIONAL
Enrollment
8
Centre Hospitalier Universitaire de Saint Etienne
Saint-Etienne, France
high frequency
measured with the holter
Time frame: One month after the hypno-analgesic therapeutic program
composite score of Francis
severity scale of syndrome (pain intensity)
Time frame: One month after the hypno-analgesic therapeutic program
Pediatric Quality of Life inventory
Time frame: One month after the hypno-analgesic therapeutic program
a chronic abdominal pain scale
adaptation of Francis composite scale for chronic abdominal pain
Time frame: One month after the hypno-analgesic therapeutic program
a severity of functional dyspepsia scale
adaptation of Francis composite scale for functional dyspepsia
Time frame: One month after the hypno-analgesic therapeutic program
a severity of abdominal migraine scale
adaptation of Francis composite scale for abdominal migraine
Time frame: One month after the hypno-analgesic therapeutic program
SDNN (standard deviation of all NN intervals)
measured with the holter
Time frame: One month after the hypno-analgesic therapeutic program
SDANN (standard deviation of the averages of NN intervals in all 5 min segments of the entire recording)
measured with the holter
Time frame: One month after the hypno-analgesic therapeutic program
RMSSD (the square root of the mean of the sum of the squares of difference between adjacent NN intervals)
measured with the holter
Time frame: One month after the hypno-analgesic therapeutic program
pNN50 (the number of pairs of adjacent NN intervals differing by more than 50 ms dived by the total number of all NN intervals)
measured with the holter
Time frame: One month after the hypno-analgesic therapeutic program
TP (total power)
measured with the holter
Time frame: One month after the hypno-analgesic therapeutic program
VLF (very low frequency component)
measured with the holter
Time frame: One month after the hypno-analgesic therapeutic program
LF (low frequency component)
measured with the holter
Time frame: One month after the hypno-analgesic therapeutic program
ratio LF/ HF
measured with the holter
Time frame: One month after the hypno-analgesic therapeutic program
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