Everolimus-Eluting Bioresorbable Scaffolds Versus Everolimus-Eluting Metallic Stents for Diffuse Long Coronary Artery Disease

Inclusion Criteria: * Age 18 and more * Diffuse long native coronary artery stenosis (\>50% by visual estimate) with lesion length of more than 40 mm requiring at least 2 overlapped stents with a reference-vessel diameter of 2.5 to 3.75 mm on visual assessment * Patients with silent ischemia, stable or unstable angina pectoris, and acute myocardial infarction including NSTEMI or STEMI * The patient or guardian agrees to the study protocol and the schedule of clinical follow-up, and provides informed, written consent, as approved by the appropriate Institutional Review Board/Ethical Committee of the respective clinical site Exclusion Criteria: * Subject has known hypersensitivity or contraindication to device material and its ingredients (everolimus, poly(L-lactide), poly(DL-lactide), lactide, lactic acid) and cobalt, chromium, nickel, platinum, tungsten, acrylic, and fluoro polymers that cannot be adequately premedicated * Subject has known allergic reaction, hypersensitivity, or contraindication to aspirin; to clopidogrel and prasugrel and ticagrelor; or to heparin and therefore cannot be adequately treated with study medication * An elective surgical procedure is planned that would necessitate interruption of antiplatelet drugs within 12 m after the procedure * STEMI requiring primary percutaneous coronary intervention * Cardiogenic shock * Restenotic lesions * Left main * Extreme angulation (≥90°) or excessive tortuosity (≥two 45° angles) proximal to or within the target lesion * Heavy calcification proximal to or within the target lesion * Compromised left ventricular dysfunction (LVEF \<30%) * At the time of screening, the subject has a malignancy that is not in remission * Terminal illness with life expectancy \<1 year * Patients who are actively participating in another drug or device investigational study, which have not completed the primary endpoint follow-up period * Patient's pregnant or breast-feeding or child-bearing potential