Effect of Intravenous Magnesium During Robot Assisted Prostatectomy

Ajou University School of Medicine60 enrolled

Overview

The primary purpose of this study is to investigate the effect of intravenous magnesium on blood pressure after Trendelenburg position during robot assisted prostatectomy. The secondary purpose of this study is to investigate the effect of intravenous magnesium on pain after robot assisted prostatectomy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Prostatic Neoplasms

Interventions

Magnesium SulfateDRUG

adminstration of intravenous magnesium as bolus of 50 mg/kg, followed by continuous infusion at rate of 10 mg/kg/h

Normal salineDRUG

the same bolus and infusion volumes of normal saline

Eligibility

Sex: MALEMin age: 60 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Robot assisted prostatectomy Exclusion Criteria: * Allergy to magnesium * Chronic pain * Chronic opioid use * Chronic NSAID use * Renal dysfunction * Liver dysfunction * Cardiac arrythmia * Seizure

Locations (1)

Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine

Suwon, Seoum, South Korea

Outcomes

Primary Outcomes

Mean blood pressure

Time frame: Up to 2 hours after Trendelenburg position

Secondary Outcomes

Postoperative pain

pain assessment using visual analog scale

Time frame: Up to 24 hours after surgery end

Data from ClinicalTrials.gov

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