Evaluation of Sleep Apnea and Cardiac Rhythm Abnormalities After Surgery Under General Anesthesia

University Hospital, Grenoble120 enrolled

Overview

Higher risk of cardiac and respiratory post-operative events is observed in patients with unrecognised Obstructive Sleep Apnea (OSA). The efficiency of a simple method of OSA screening by analysing ventilation with measurement of nose pressure and nocturnal hypoxemia (oxygen desaturation index) will be assessed. These sleep respiratory analyses will be compared with the research of arrhythmia, in order to show if they are linked to the hypoxemia events. Aggravation of nocturnal respiratory disorder and higher incidence of cardiac and respiratory postoperative complications will be assessed in OSA patients.

Study Type

INTERVENTIONAL

Allocation

Purpose

SCREENING

Masking

NONE

Enrollment

120

Conditions

Obstructive Sleep Apnea Arrhythmia

Interventions

Eligibility

Sex: ALLMin age: 45 YearsMax age: 99 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * orthopaedic, urologic, vascular, digestive surgery * under general anaesthesia or sedation * age \> 45 years old * STOP-BANG score\>3 Exclusion Criteria: * Head and neck surgery, planned prolonged mechanical ventilation after surgery (\>24h) * Severe COPD * Post-operative ICU planned * Diagnosed OSA or other sleep disorder breathing

Outcomes

Primary Outcomes

Change from baseline in heart rhythm troubles linked to hypoxemia events

Heart rhythm troubles will be assessed 3 times: * First time = baseline assessment, during one night before surgery * second assessment will occur during the first night after surgery * last assessment will take place during the third night after surgery

Time frame: Before surgery and at first and third night after surgery

Secondary Outcomes

Change from baseline in severity of OSA defined by the oxygen saturation index

OSA will be assessed 3 times: * First time = baseline assessment, during one night before surgery * second assessment will occur during the first night after surgery * last assessment will take place during the third night after surgery oxygen saturation index \> 10 mandatory for the study oxygen saturation index \> 40 : result qualified severe

Time frame: Before surgery and at first and third night after surgery

Aggravation of cardiac events linked to hypoxemia

Time frame: After surgery from night 1 to night 15 maximum

Change from baseline OSA prevalence and cardiorespiratory complications after surgery

Time frame: Before surgery and at first and third night after surgery