Saturated Fatty Acids and HDL Metabolism

Inclusion Criteria: * Apparently healthy men and post-menopausal women (post-menopausal for at least one year) as judged by study physician * BMI ≥ 18.0 and ≤ 30.0 kg/m2 * Aged between 45 and 70 years * Willing to comply to study protocol during study * Having a general practitioner * Agreeing to be informed about medically relevant personal test-results by a physician * Informed consent signed * Accessible veins on arms as determined by examination at screening Exclusion Criteria: * Having a medical condition which might impact study measurements * Use of over-the-counter and prescribed medication, which may interfere with study measurements * Use of oral antibiotics in 40 days or less prior to the start of the study; * Use of food supplements or plant-sterol/stanol-enriched foods or supplements in the three months prior to the screening and/or during the study; * Reported alcohol consumption ≥ 10 units/week (female) or ≥ 14 units/week (male); * Reported intense sporting activities ≥ 10 hours/week; * Reported weight loss or gain of 3 kg or more during a period of 2 months prior to screening * Regular smokers (at least one cigarette (or equivalent) daily or \>7 cigarettes (or equivalent) weekly. Smokers who cannot comfortably restrain from smoking for up to 2 days will also be excluded * Reported dietary habits: medically prescribed diet, allergy/intolerance to test products that will be provided during the study * Blood donation in the past 3 months * Drug abuse * Reported participation in another nutritional or biomedical trial 3 months prior to screening * Fasting triacylglycerol concentrations at screening: ≥ 4.5 mmol/L * Serum lipids: treatment recommended according to the "Multidisciplinary guidelines Cardiovascular risk management" * Fasting HbA1c ≥ 48 mmol/mol (or 6.5%)