Postprandial Effects of High-fat Meals With Different Dairy Products on Lipid Metabolism and Inflammation

Inclusion Criteria: * The study will include both men and women aged 18-70 years with the aim of an even age and gender balance. * Participants in the healthy group will need to have a body mass index (BMI) between 18.5 - 24.9 kg/m2 and a waist circumference (WC) of \<94 cm for men and\<80 cm for women. * Participants in the obese group will need to have a BMI of ≥25 kg/m2 and a waist circumference of ≥94 cm for men and ≥80 cm for women. * All subjects must be willing to eat three slices of bread with a dairy product and jam as breakfast. Exclusion Criteria: * BMI \<18.5 kg/m2 or \>25 kg/m2 in the healthy group and \<25 kg/m2 in the obese group * WC ≥94 for men and ≥80 cm for women in the healthy group, \<94/80 cm for men/women in the obese group * Weight change of ± 5 % of body weight in the last three months * TG ≥1.3 mmol/L in the healthy group * CRP \>10 mg/L * Total cholesterol \>6.1 mmol/L for subjects 18-29 years, \>6.9 mmol/L for subjects 30-49 years and \>7.8 mmol/L for subjects ≥50 years old * Blood pressure \>160/100 mm Hg * Comorbidities including diabetes type I and II (blood glucose ≥7 mmol/L fasting), coronary heart disease, haemophilia, anaemia (hemoglobin \<120 gram/L), gastro intestinal disease and hyperthyroidism (TSH \>4 mU/L) * Pregnant or lactating * Allergic or intolerant to gluten, milk protein and/or lactose * Use of medications affecting lipid metabolism or inflammation * Unwilling to seponate omega-3 rich supplements four weeks prior to screening and during the study period * Hormone treatment (stabile dose of contraception or thyroxin for the last three months excepted) * Blood donation two months prior to test day 1 or during the study period * Tobacco smoking * Excessive regular alcohol consumption (\>40 grams per day) or prior to the test day