Breath Volatile Organic Compounds Patterns of Lung Transplant Patients With Chronic Lung Allograft Dysfunction

Prof. Dr. Jens Hohlfeld75 enrolled

Overview

It's the aim of this study to clarify, whether the non-invasive assessment of breath can serve as a novel clinical tool to assist in the diagnosis of CLAD. If different stages of BOS can be discriminated by the level of certain VOCs than there would also be a potential to actually predict the development at an early stage and would enable an earlier intervention.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Chronic Lung Allograft Dysfunction (CLAD)

Interventions

Collection of exhaled breath volatile organic compoundsOTHER

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Outpatient bilateral lung transplant recipients including combined transplants Exclusion Criteria: * Active Smoking Oxygen therapy Infection with multi or pan-resistant bacteria

Locations (1)

Hannover Medical School

Hanover, Germany

Outcomes

Primary Outcomes

Concentration of exhaled breath volatile organic compounds

Time frame: one sample will be collected between 6 month and 20 years after lung transplantation

Data from ClinicalTrials.gov

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