A Study Evaluating the Efficacy of a Single Injection Autologous Adipose Derived Mesenchymal Stromal Cells in Patients With Knee Osteoarthritis

Inclusion Criteria: * Symptomatic mild to moderate osteoarthritis (OA) of the index knee as defined by the American college of Rheumatology (ACR) * Must meet pain criteria at the time of screening/baseline visit since at least half of the days in the previous month * NSAID washout of at least 2 days before screening/baseline Exclusion Criteria: * Previous treatments acting on cartilage or bone metabolism * Received intra-articular injection of corticosteroids, platelet rich plasma or hyaluronic acid within the previous 6 months, * Significant trauma or surgery to the index knee within the last year or arthroscopy of the index knee within 12 months of screening. * Kellgren-Lawrence Grade 1 or 4 in the index knee on any incidences. * Osteoarthritis causing significant pain in any joint other than the identified knee, i.e., pain in hip, or contralateral knee (≥ 20 mm pain) as confirmed by a separate VAS at baseline for any other painful joint concerned * History of joint replacement of the knee or hip within the previous 12 months