A Study to Characterize the Cardiac Phenotype of Individuals With Friedreich's Ataxia (CARFA Study)

Inclusion Criteria (Friedreich's Ataxia): * Males and females; * ≥ 18 years old; * Willing and able to provide informed consent; * Definitive diagnosis of FA, based on clinical phenotype and genotype; * With a hypertrophic cardiomyopathy; * Ability to complete study assessments. Exclusion Criteria (Friedreich's Ataxia): * Symptoms of cardiac failure; * Moderate to severe atrial or ventricular arrhythmias; * History of angina pectoris; * Inability to undergo cardiac MRI; * Clinical history or evidence of diabetes; * Abnormal kidney function; * Females who are pregnant or nursing; * Receipt of an investigational drug within 30 days or 5 half-lives, or active enrollment in an investigational medication or device study; * Inability to sit with back support; * Inability to undergo exercise test; * Inability to comply with all study requirements; * Unaffiliated to any French health insurance or equivalent. Inclusion Criteria (Healthy Volunteers): * Healthy males and females; * ≥ 18 years old; * Willing and able to provide informed consent; * Age and gender matched to the Friedreich's Ataxia group; * Ability to complete study assessments. Exclusion Criteria (Healthy Volunteers): * Inability to undergo cardiac MRI; * Clinical history or evidence of diabetes; * Abnormal kidney function; * Females who are pregnant or nursing; * Receipt of an investigational drug within 30 days or 5 half-lives, or active enrollment in an investigational medication or device study; * Inability to undergo exercise test; * Inability to comply with all study requirements; * Unaffiliated to any French health insurance or equivalent.