Feasibility of the Preparation of an Advanced Therapy Medicinal Product for Dental Pulp Regeneration

Inclusion Criteria: * Patients aged from 8 to 15 years, with at least one tooth affected by a carious process, * Patients aged from 8 to 15 years with major trauma preventing the maintenance of the tooth in the arch * Patients aged from 16 to 20 years requiring avulsion germs wisdom teeth, * Ability to carry out the extraction of pulp chamber content * Signature of informed consent (from the patient and his guardian) * Indication that the subject has understood the purpose and procedures required by the study and agrees to participate in the study and comply with the requirements and limitations inherent in this study, * Patient with French social insurance. Exclusion Criteria: * Lack of ability to collect the dental pulp, * Presence of necrosis in pulp complex or the possibility of preserving the pulp through appropriate techniques, * Legal incapacity or limited legal capacity * Patient unlikely to cooperate in the study and / or low cooperation anticipated by the investigator, * Patient without health insurance, * The patient is in the period of exclusion of another study, * Patients with congenital pathology of dental pulp (amelogenesis and dentinogenesis imperfect) * Patient with intrapulpal calcification or violations of pulp obliteration * Teeth having external or internal inflammatory resorption * Teeth diagnosed with pulp necrosis process * Teeth undergoing fragmentation for their avulsion * Time of pulp air exposition \> 2 hours (risk of bacterial contamination)