Epilepsy is a devastating chronic disease due to multiple causes that affect close to 50% of the world's population. Although effective, epilepsy surgery fails in many cases, the percentage of patients free from crisis on a long term (≥ 5 years) varies from 27% to 66% according to the kind of epilepsy. It is in this context that EPISTIM is interesting, and its aims isb a better electrophysiology delimiting of cortical networks that imply the genesis of seizures with the aim to improove surgery results. This study will rely on the intracerebral records and on corticales electrical stimulation as they are currently routinely used by epileptic patients candidates for surgery.
Study Type
INTERVENTIONAL
Allocation
NA
Masking
NONE
Enrollment
45
Visual analysis : in order to define the level of cortical resections. Epileptogenic maps : calculated for each crisis and for all crisis in general. Connectivity maps : calculated for each site stimulated at low-frequency. Post-operative evaluation : in order to assess the extent of resection.
UniversityHospitalGrenoble
La Tronche, France
RECRUITINGVisual analysis
Visual analysis : in order to define the level of cortical resections.
Time frame: up to one hour
Epileptogenic maps
Epileptogenic maps : calculated for each crisis and for all crisis in general.
Time frame: up to 10 min
Connectivity maps
Connectivity maps : calculated for each site stimulated at low-frequency.
Time frame: up to 10 min
MRI
Post-operative evaluation : in order to assess the extent of resection. MRI : 3D-T1
Time frame: up to one hour
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