Hemodynamic Response to Intubation

Ufuk University60 enrolled

Overview

This study investigates the effects of dexmedetomidine and esmolol given intravenously before intubation on sympathetic response caused by intubation itself. Half the patients will recevice dexmedetomidine and the other half will receive dexmedetomidine. Ischemia modified albumine levels will be measured

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

TRIPLE

Enrollment

Conditions

Intubation

Interventions

DexmedetomidineDRUG

EsmololDRUG

PlaceboDRUG

normal saline

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients undergoing elective surgery under general anesthesia Exclusion Criteria: * Patient refusal * Morbid obesity (BMI\>30) * Advanced systemic disease * Hypoalbumiemia * beta-blocker usage * Anticipated difficult ventilation and/or intubation

Locations (1)

Ufuk University Hospital

Ankara, Turkey (Türkiye)

RECRUITING

Outcomes

Primary Outcomes

ischemia modified albumine

ischemia modified albumine levels will be measured as a response to intubation

Time frame: 10 minutes after endotracheal intubation

Central Contacts

Perihan Ekmekçi, Ass Prof

CONTACT

+903122044000 erdogduperi@gmail.com

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.