Incidence and Severity of Postoperative Sore Throat And Intubation Response by Using Different Devices for Endotracheal Intubation

King Saud University420 enrolled

Overview

Postoperative sore throat (POST) is a common problem following the use of endotracheal intubation during general anaesthesia. It leads to dissatisfaction and discomfort after surgery and can delay a patient's return to normal routine activities. POST has been rated by patients as the eighth most adverse effect in the postoperative period. The incidence of sore throat after endotracheal intubation varies from 14.4-90%. Laryngoscopy and tracheal intubation also leads to hemodynamic stress response. The response can be deleterious in patient with or without cardiac disease. It is related to the degree of manipulation of the airway during endotracheal intubation and has been studied during intubation for some equipment used for endotracheal intubation

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

QUADRUPLE

Enrollment

420

Conditions

Pharyngitis Endotracheal Intubation Pain

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * After signing of the informed consent, * ASA physical status I and II * Mallampati class 1\& 2, * BMI \< 35, * Undergoing elective surgical procedures (not exceeding two hours in duration) requiring ET intubation Exclusion Criteria: * Patients undergoing day case, * bariatric, cardiac, nasal, oral or head \& neck surgeries, * requiring placement of throat pack or nasogastric/ orogastric tube, * patients assigned to rapid sequence induction, * hoarseness, * patients with anticipated difficult intubation, * history of recent upper respiratory tract infection, * history of difficult intubation * psychiatric disorders hindering proper evaluation, * use of steroids (oral or inhalational) or non-steroidal anti-inflammatory drugs within one week of surgery or previous surgery within last two weeks

Outcomes

Primary Outcomes

Incidence of post operative sore throat

Time frame: 0 hours after surgery

Incidence of post operative sore throat

Time frame: 6 hours after surgery

Incidence of post operative sore throat

Time frame: 12 hours after surgery

Incidence of post operative sore throat

Time frame: 24 hours after surgery

Severity of post operative sore throat

Time frame: 0 hours after surgery

Severity of post operative sore throat

Time frame: 6 hours after surgery

Severity of post operative sore throat

Time frame: 12 hours after surgery

Severity of post operative sore throat

Time frame: 24 hours after surgery