Absorption and Systematic Pharmacokinetics of Topically Applied IDP-120 Gel

Key Inclusion Criteria: * Male or female between the ages of 9 and \<17 (16 years 11 months) * Written and verbal informed consent must be obtained. Subjects less than age of consent must sign an assent for the study and a parent or legal guardian must sign the informed consent. * Subject must have a score of 3 (moderate) or 4 (severe) on the Evaluator's Global Severity assessment. * Subject with facial acne inflammatory lesion count no less than 20 but no more than 40. * Subject with facial acne non-inflammatory lesion count no less than 20 but no more than 100. Key Exclusion Criteria: * Use of an investigational drug or device within 30 days of enrollment, previous participation in a research study with IDP-120 Gel, or participation in a research study concurrent with this study. * Any dermatological conditions on the face that could interfere with clinical evaluations such as acne conglobate, acne fulminans, secondary acne, perioral dermatitis, clinically significant rosacea, gram-negative folliculitis. * Any underlying disease or some other dermatological condition of the face that requires the use of interfering topical or systemic therapy or makes evaluations and lesion counts inconclusive. * Subjects with a facial beard or mustache that could interfere with the study assessments * Subjects with more than 2 facial nodules.